BDBM50049357 4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-phenethyl-piperidine::CHEMBL352272

SMILES Fc1ccc(cc1)C(OCCC1CCN(CCc2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=TWJWHTGPMGTMPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049357   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Organix

Curated by ChEMBL
LigandPNGBDBM50049357(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-phen...)
Affinity DataIC50:  19.9nMAssay Description:Binding affinity at dopamine transporter from rat striatal membrane tissue by [3H]-CFT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Organix

Curated by ChEMBL
LigandPNGBDBM50049357(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-phen...)
Affinity DataIC50:  31.9nMAssay Description:Binding affinity at serotonin transporter from rat brain striatal membrane by [3H]-citalopram displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed