BDBM50049363 4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-phenyl-propyl)-piperidine::CHEMBL77867

SMILES Fc1ccc(cc1)C(OCCC1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=QWAAKIRPIKMRGP-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049363   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT) by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter of rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  68nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]-RTI-55More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Organix

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataIC50:  55nMAssay Description:Binding affinity at serotonin transporter from rat brain striatal membrane by [3H]-citalopram displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataIC50:  16.7nMAssay Description:Binding affinity at dopamine transporter from rat striatal membrane tissue by [3H]-CFT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed