BDBM50049413 CHEMBL3313945::US11401286, Example 52

SMILES CCc1nc(Nc2ccc(CC#N)cc2)nc(n1)-c1cccc(Cl)c1

InChI Key InChIKey=LQNZLLWTKCWUTO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049413   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50:  165nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50:  7nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners

US Patent
LigandPNGBDBM50049413(CHEMBL3313945 | US11401286, Example 52)
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In DepthDetails US Patent