BDBM50049418 CHEMBL3315275::US11401286, Example 59
SMILES CCc1nc(Nc2ccc(cc2)C(C)C(O)=O)nc(n1)-c1cccc(Cl)c1
InChI Key InChIKey=OFISQNBGNCPVKB-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50049418
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D](Homo sapiens (Human))
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Northern Illinois University
Curated by ChEMBL
Northern Illinois University
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair