BDBM50049505 2-Methyl-1-nitro-4-(4,6,6-trimethyl-2-methylene-cyclohex-3-enylmethyl)-benzene::CHEMBL299512

SMILES CC1=CC(=C)C(Cc2ccc(c(C)c2)[N+]([O-])=O)C(C)(C)C1

InChI Key InChIKey=ARDKBOYBRBHJCL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049505   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049505(2-Methyl-1-nitro-4-(4,6,6-trimethyl-2-methylene-cy...)
Affinity DataKi:  29nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049505(2-Methyl-1-nitro-4-(4,6,6-trimethyl-2-methylene-cy...)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049505(2-Methyl-1-nitro-4-(4,6,6-trimethyl-2-methylene-cy...)
Affinity DataKi:  6.81E+3nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049505(2-Methyl-1-nitro-4-(4,6,6-trimethyl-2-methylene-cy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049505(2-Methyl-1-nitro-4-(4,6,6-trimethyl-2-methylene-cy...)
Affinity DataIC50:  510nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed