BDBM50049534 CHEMBL3319108

SMILES CC(C(=O)NCc1ccc(nc1-c1ccc(F)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key InChIKey=DBVDMBHCMBBPSR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50049534   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50049534(CHEMBL3319108)
Affinity DataKi:  0.400nMAssay Description:Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced channel activation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50049534(CHEMBL3319108)
Affinity DataKi:  0.840nMAssay Description:Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of NADA-induced channel activation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50049534(CHEMBL3319108)
Affinity DataKi:  26nMAssay Description:Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of 45 degC heat-induced channel activation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50049534(CHEMBL3319108)
Affinity DataKi:  131nMAssay Description:Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of pH-induced channel activation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed