BDBM50049823 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile::4-Amino-7-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile::4-Amino-7-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile(toyocamycin)::4-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile::Ara-toyocamycine::CHEMBL99668::TOYOCAMYCIN::Unamycin B::cid_247955
SMILES Nc1ncnc2n(cc(C#N)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InChI Key InChIKey=XOKJUSAYZUAMGJ-WOUKDFQISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50049823
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 310nMAssay Description:Inhibition of human adenosine kinase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human adenosine kinaseMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of DOT1L (unknown origin) using chicken nucleosome as substrate in presence of [3H]SAM incubated for 1 hr by TopCount methodMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 9.00E+4nMAssay Description:Binding affinity to human truncated HSC70 NBD (1 to 381 residues) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 309nMAssay Description:Concentration required for 50% inhibition of the adenosine kinase (AK) activity.More data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 9.12E+4nMAssay Description:Binding affinity to human truncated HSC70 NBD (1 to 381 residues) by SPR analysisMore data for this Ligand-Target Pair