BDBM50050396 6-(Naphthalen-1-ylsulfanylmethyl)-pteridine-2,4-diamine::CHEMBL22434

SMILES Nc1nc(N)c2nc(CSc3cccc4ccccc34)cnc2n1

InChI Key InChIKey=BWEWHULNTMEGEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50050396   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050396(6-(Naphthalen-1-ylsulfanylmethyl)-pteridine-2,4-di...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50050396(6-(Naphthalen-1-ylsulfanylmethyl)-pteridine-2,4-di...)
Affinity DataIC50:  9.50E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050396(6-(Naphthalen-1-ylsulfanylmethyl)-pteridine-2,4-di...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050396(6-(Naphthalen-1-ylsulfanylmethyl)-pteridine-2,4-di...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed