BDBM50050584 1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-4-propoxy-phenyl]-3-(4-fluoro-phenyl)-urea::CHEMBL42988
SMILES CCCOc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1
InChI Key InChIKey=DUHSRERDUDMRPS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50050584
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair