BDBM50050590 1,3-Dimethyl-6-[5-(4-methyl-thiazol-2-yl)-2-propoxy-phenyl]-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one::CHEMBL45039
SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1nc(C)cs1
InChI Key InChIKey=KXNVHENJOJLCLG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50050590
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair