BDBM50050592 CHEMBL46621::N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-4-propoxy-phenyl]-2-(4-methyl-piperazin-1-yl)-acetamide

SMILES CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1

InChI Key InChIKey=DMEMDJCFIUUGIZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050592   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050592(CHEMBL46621 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataEC50:  400nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050592(CHEMBL46621 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed