BDBM50050597 1-Ethyl-3-methyl-6-(5-nitro-2-propoxy-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one::CHEMBL298295

SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)[N+]([O-])=O

InChI Key InChIKey=DRKXFOGKAMGWJN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050597   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050597(1-Ethyl-3-methyl-6-(5-nitro-2-propoxy-phenyl)-1,5-...)
Affinity DataEC50:  50nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050597(1-Ethyl-3-methyl-6-(5-nitro-2-propoxy-phenyl)-1,5-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed