BDBM50050649 CHEMBL444832::{(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylcarbamoyl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@](C)(Cc1ccccc1)C(=O)NCCCCCCCNC(N)=O
InChI Key InChIKey=BYVRLIUFCGUMSP-XYFQYJLHSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50050649
Affinity DataIC50: 9nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for NK1 receptor binding sites in human lymphoma IM9 cells by using [125I]-Bolton-Hunter substance P as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 6.54E+3nMAssay Description:Binding affinity for NK2 receptor binding sites in membranes prepared from hamster urinary bladder by using [125I]NKA as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 6.54E+3nMAssay Description:Inhibitory activity against Tachykinin receptor 2 in membranes prepared from hamster urinary bladder labeled with [125 I] NKAMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Compound was tested for binding affinity against human Tachykinin receptor 3 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibitory activity against cloned human Tachykinin receptor 3 in CHO cells labeled with [125I][MePhe7]-NKBMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in human lymphoma IM9 cells labeled with [125 I] Bolton-Hunter substance PMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against cloned human Tachykinin receptor 3 in CHO cells labeled with [125I][MePhe7]-NKBMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [125I][MePhe]-NKB from human NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity towards human Tachykinin receptor 3 stably expressed in CHO cells using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair