BDBM50051375 (6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-deca-4,8-dienyl)-1,2,3,5,6,7,8,8a-octahydro-isoquinolin-6-ol::CHEMBL76239

SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#7]-1-[#6]-[#6]=[#6]2C([#6])([#6])[#6@@H](-[#8])-[#6]-[#6][C@]2([#6])[#6]-1

InChI Key InChIKey=CKIQSCJROIUFAT-XAYFZMMHSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051375   

TargetLanosterol synthase(Rattus norvegicus)
Laboratoires Fournier

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataKi:  300nMAssay Description:Binding affinity towards competitive inhibition against rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Laboratoires Fournier

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards noncompetetive inhibition against rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Laboratoires Fournier

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed