BDBM50051939 CHEMBL3322590

SMILES Fc1ccccc1-c1c[nH]cc(C(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1=O

InChI Key InChIKey=QBOWGZQRUNUQGL-ZDLGFXPLSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50051939   

TargetCytochrome P450 1A2(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using 3-Cyano-7-ethoxycoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP2C9 (unknown origin) using Vivid OOMR substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using 3-Cyano-7-ethoxycoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50:  26nMAssay Description:Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using Vivid OOMR substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG channel by hERG Tracer Red based fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50:  100nMAssay Description:Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051939(CHEMBL3322590)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) using 3-Cyano-7-ethoxycoumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed