BDBM50052681 CHEMBL114890::N-[3-((Z)-2-Benzo[1,3]dioxol-5-yl-2-cyano-vinyl)-4-methyl-phenyl]-3-cyclohexyl-propionamide

SMILES Cc1ccc(NC(=O)CCC2CCCCC2)cc1\C=C(/C#N)c1ccc2OCOc2c1

InChI Key InChIKey=XNVQDLQCRAIBMQ-LPYMAVHISA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052681   

TargetLow-density lipoprotein receptor(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50052681(CHEMBL114890 | N-[3-((Z)-2-Benzo[1,3]dioxol-5-yl-2...)
Affinity DataEC50:  700nMAssay Description:Concentration at which one-half of the maximum Low density lipoprotein receptor is upregulated in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed