BDBM50052734 8-Chloro-3-[(E)-3-(4-dimethylamino-phenyl)-allyl]-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL114228

SMILES CN(C)c1ccc(\C=C\CN2CCc3cc(Cl)c(O)cc3C(C2)c2ccccc2)cc1

InChI Key InChIKey=WNLBCBQNLPTEAJ-VOTSOKGWSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052734   

TargetD(1A) dopamine receptor(RAT)
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50052734(8-Chloro-3-[(E)-3-(4-dimethylamino-phenyl)-allyl]-...)
Affinity DataKi:  18nMAssay Description:Dopamine receptor D1 antagonistic activity as ability to block dopamine-stimulated adenylate cyclase in rat caudateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50052734(8-Chloro-3-[(E)-3-(4-dimethylamino-phenyl)-allyl]-...)
Affinity DataKi:  60.7nMAssay Description:Compound was tested for the Binding affinity against Human cloned Dopamine receptor D1 by Radio ligand ([3H]-SCH-23390) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50052734(8-Chloro-3-[(E)-3-(4-dimethylamino-phenyl)-allyl]-...)
Affinity DataKi:  345nMAssay Description:Affinity for Dopamine receptor D2 binding measured by sulpiride 23390 to rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed