BDBM50052888 2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine::CHEMBL323692

SMILES C1CNc2ccccc2CN1

InChI Key InChIKey=MLXBHOCKBUILHN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50052888   

LigandPNGBDBM50052888(2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine | CHE...)
Affinity DataKi:  3.77E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50052888(2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine | CHE...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50052888(2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine | CHE...)
Affinity DataKi:  2.82E+4nMAssay Description:In vitro for inhibition of Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed