BDBM50053688 CHEMBL3318856::US9328106, 380

SMILES Cn1ncc(NC(=O)c2csc(n2)-c2c(F)cc(cc2F)[C@H]2CCCO2)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=QEZYBTCAQWROBF-SMOSDQRPSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053688   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50053688(CHEMBL3318856 | US9328106, 380)
Affinity DataKi:  0.0710nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50053688(CHEMBL3318856 | US9328106, 380)
Affinity DataKi:  0.0710nM ΔG°:  -13.8kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
In DepthDetails US Patent