BDBM50054426 7-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::CHEMBL127277

SMILES OC1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21

InChI Key InChIKey=PLHXPQPLYRWYLK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50054426   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50054426(7-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of Protein Kinase C(PKC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50054426(7-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50:  3.83E+3nMAssay Description:Inhibition of Cyclin B-cyclin-dependent kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50054426(7-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054426(7-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of protein kinase AMore data for this Ligand-Target Pair
In DepthDetails