BDBM50054728 1,4-Bis-(3-phenyl-propyl)-piperazine::CHEMBL346409

SMILES C(CN1CCN(CCCc2ccccc2)CC1)Cc1ccccc1

InChI Key InChIKey=NTNUZVAWJJOFJL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054728   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054728(1,4-Bis-(3-phenyl-propyl)-piperazine | CHEMBL34640...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054728(1,4-Bis-(3-phenyl-propyl)-piperazine | CHEMBL34640...)
Affinity DataIC50:  7.76E+3nMAssay Description:Binding against Dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054728(1,4-Bis-(3-phenyl-propyl)-piperazine | CHEMBL34640...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054728(1,4-Bis-(3-phenyl-propyl)-piperazine | CHEMBL34640...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed