BDBM50054741 (2S,5R)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-2,5-dimethyl-4-(3-phenyl-propyl)-piperazine::CHEMBL142545

SMILES C[C@@H]1CN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)[C@@H](C)CN1CCCc1ccccc1

InChI Key InChIKey=CNCNZYATGYMZNQ-RPWUZVMVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054741   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054741((2S,5R)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl...)
Affinity DataIC50:  40nMAssay Description:Binding against Dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054741((2S,5R)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl...)
Affinity DataIC50:  459nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054741((2S,5R)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed