BDBM50056258 (3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[10.3.1]hexadeca-1(15),12(16),13-triene-6-carboxylic acid::CHEMBL148840

SMILES OC(=O)[C@@H]1CCCCCc2cccc(C[C@@H](CS)C(=O)N1)c2

InChI Key InChIKey=YSERSWXWBJFHEC-GJZGRUSLSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056258   

TargetNeprilysin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056258((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[10.3....)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056258((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[10.3....)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required to inhibit thermolysin (TLN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056258((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[10.3....)
Affinity DataIC50:  8nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Universite£

Curated by ChEMBL
LigandPNGBDBM50056258((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[10.3....)
Affinity DataIC50:  4nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Universite£

Curated by ChEMBL
LigandPNGBDBM50056258((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[10.3....)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration required to inhibit Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed