BDBM50056466 CHEMBL3334727
SMILES CC(C)[C@@H](NC(=O)N[C@H]1CC[C@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1
InChI Key InChIKey=OHILZTIHDULTLZ-KTIHBUSBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50056466
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 5.70E+3nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair