BDBM50056466 CHEMBL3334727

SMILES CC(C)[C@@H](NC(=O)N[C@H]1CC[C@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1

InChI Key InChIKey=OHILZTIHDULTLZ-KTIHBUSBSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056466   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50056466(CHEMBL3334727)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MIP-1alpha from CCR1 in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50056466(CHEMBL3334727)
Affinity DataEC50:  5.70E+3nMAssay Description:Transactivation of human full-length PXR transfected in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50056466(CHEMBL3334727)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at CCR1 receptor in human THP1 cells assessed as inhibition of MIP-1alpha induced chemotaxis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed