BDBM50057160 3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methanesulfonyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10661

SMILES COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(cc1)S(C)(=O)=O)c1ccc2OCOc2c1

InChI Key InChIKey=IBHRHASLMMYFEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057160   

TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057160(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methanesulf...)
Affinity DataIC50:  3.00E+3nMAssay Description:Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057160(3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methanesulf...)
Affinity DataIC50:  4nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed