BDBM50057178 CHEMBL10847::Sodium; (Z)-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-3-methyl-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate

SMILES COc1cc(cc2OCOc12)C(\C([O-])=O)=C(/Cc1ccc(OC)c(OC)c1OC)C(=O)c1ccc(OC)c(C)c1

InChI Key InChIKey=ICAHNKLYQDWFQQ-QQTULTPQSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057178   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057178(CHEMBL10847 | Sodium; (Z)-2-(7-methoxy-benzo[1,3]d...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057178(CHEMBL10847 | Sodium; (Z)-2-(7-methoxy-benzo[1,3]d...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Endothelin B receptor mediated (ET-3) release of arachidonic acid from human cloned receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed