BDBM50057213 CHEMBL10905::Potassium; (Z)-3-(4-acetylamino-benzyl)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate

SMILES COc1ccc(cc1)C(=O)C(\Cc1ccc(NC(C)=O)cc1)=C(/C([O-])=O)c1ccc2OCOc2c1

InChI Key InChIKey=OCUILRUINFKWQH-LVWGJNHUSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057213   

TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057213(CHEMBL10905 | Potassium; (Z)-3-(4-acetylamino-benz...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of Endothelin B receptor mediated (ET-3) release of arachidonic acid from human cloned receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057213(CHEMBL10905 | Potassium; (Z)-3-(4-acetylamino-benz...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed