BDBM50057580 4-(5-Indan-5-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide::CHEMBL29500

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc2CCCc2c1)C(F)(F)F

InChI Key InChIKey=PBMQINHMSIZXSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057580   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057580(4-(5-Indan-5-yl-3-trifluoromethyl-pyrazol-1-yl)-be...)
Affinity DataIC50:  1.52E+4nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057580(4-(5-Indan-5-yl-3-trifluoromethyl-pyrazol-1-yl)-be...)
Affinity DataIC50:  30.9nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057580(4-(5-Indan-5-yl-3-trifluoromethyl-pyrazol-1-yl)-be...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed