BDBM50058453 2-Ethyl-1-(4-trifluoromethoxy-phenyl)-isothiourea; hydrochloride::CHEMBL500922::CHEMBL554651
SMILES CCSC(N)=Nc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=LDRUFSWQOURAKN-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50058453
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica
Curated by ChEMBL
Instituto De QuíMica MéDica
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica
Curated by ChEMBL
Instituto De QuíMica MéDica
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase in brain (nNOS).More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibitory activity against human vascular endothelial nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS).More data for this Ligand-Target Pair