BDBM50058945 (1S,2S,3S,4S)-3,4-Bis-[(4-phenoxy-benzyl)-propyl-carbamoyl]-cyclobutane-1,2-dicarboxylic acid::A-87049::CHEMBL445618

SMILES CCCN(Cc1ccc(Oc2ccccc2)cc1)C(=O)[C@@H]1[C@@H]([C@H]([C@H]1C(=O)N(CCC)Cc1ccc(Oc2ccccc2)cc1)C(O)=O)C(O)=O

InChI Key InChIKey=PNOGMVDDWILAMR-ZYADHFCISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058945   

TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058945((1S,2S,3S,4S)-3,4-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  37nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058945((1S,2S,3S,4S)-3,4-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibitory activity against Squalene SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed