BDBM50058999 3-(3,4-Dimethyl-benzenesulfonyl)-1-(3,4-dimethyl-phenyl)-imidazolidine-2,4-dione::CHEMBL69714

SMILES Cc1ccc(cc1C)N1CC(=O)N(C1=O)S(=O)(=O)c1ccc(C)c(C)c1

InChI Key InChIKey=RHYKGYBIOCNWTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058999   

TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058999(3-(3,4-Dimethyl-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058999(3-(3,4-Dimethyl-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058999(3-(3,4-Dimethyl-benzenesulfonyl)-1-(3,4-dimethyl-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed