BDBM50059035 3-Isobutyl-8-methoxymethyl-1-methyl-3,7-dihydro-purine-2,6-dione::3-Isobutyl-8-methoxymethyl-1-methyl-3,9-dihydro-purine-2,6-dione::3-isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione::CHEMBL307639

SMILES COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1

InChI Key InChIKey=NBLBCGUCPBXKOV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059035   

TargetPhosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059035(3-Isobutyl-8-methoxymethyl-1-methyl-3,7-dihydro-pu...)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059035(3-Isobutyl-8-methoxymethyl-1-methyl-3,7-dihydro-pu...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant PDE1A3 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059035(3-Isobutyl-8-methoxymethyl-1-methyl-3,7-dihydro-pu...)
Affinity DataIC50:  1.00E+4nMAssay Description:Evaluated for inhibitory activity against Phosphodiesterase 5 (PDE5) purified from bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed