BDBM50059688 7-[(6-Carbamimidoyl-1H-indole-3-carbonyl)-amino]-heptanoic acid::CHEMBL318493

SMILES NC(=N)c1ccc2c(c[nH]c2c1)C(=O)NCCCCCCC(O)=O

InChI Key InChIKey=VRUKHGBNBGNBNZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059688   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059688(7-[(6-Carbamimidoyl-1H-indole-3-carbonyl)-amino]-h...)
Affinity DataIC50:  100nMAssay Description:Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059688(7-[(6-Carbamimidoyl-1H-indole-3-carbonyl)-amino]-h...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059688(7-[(6-Carbamimidoyl-1H-indole-3-carbonyl)-amino]-h...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of adhesive protein binding to alphaV-beta3 vitronectin receptor using ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059688(7-[(6-Carbamimidoyl-1H-indole-3-carbonyl)-amino]-h...)
Affinity DataIC50:  650nMAssay Description:Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed