BDBM50059707 7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-heptanoic acid::CHEMBL95223

SMILES NC(=N)c1ccc2[nH]c(cc2c1)C(=O)NCCCCCCC(O)=O

InChI Key InChIKey=CZITZJPLCUWFMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059707   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059707(7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059707(7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059707(7-[(5-Carbamimidoyl-1H-indole-2-carbonyl)-amino]-h...)
Affinity DataIC50:  680nMAssay Description:Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed