BDBM50059857 CHEMBL102955::[(S)-1-[(4-Benzyloxy-benzyl)-(phenethylcarbamoyl-methyl)-carbamoyl]-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester::[(S)-1-[(4-Benzyloxy-benzyl)-(phenethylcarbamoyl-methyl)-carbamoyl]-2-(3H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCCc1ccccc1

InChI Key InChIKey=JOMJUWAAYRJJBC-DHUJRADRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059857   

LigandPNGBDBM50059857(CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059857(CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...)
Affinity DataIC50:  170nMAssay Description:Activity against FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059857(CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...)
Affinity DataIC50:  4.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed