BDBM50059961 2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-4-one::2-(3-chlorophenyl)-6-methyl-1,8-naphthyridin-4(1H)-one::CHEMBL49827::NSC-679036

SMILES Cc1cnc2nc(cc(O)c2c1)-c1cccc(Cl)c1

InChI Key InChIKey=FSWIIQLXZOJBSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059961   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  720nMAssay Description:Concentration inhibiting tubulin polymerization (ITP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  720nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed