BDBM50059966 7-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-one::CHEMBL52342

SMILES Cc1ccc2c(O)cc(nc2n1)-c1cccc2ccccc12

InChI Key InChIKey=OKZRVQQAEAXGHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059966   

TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059966(7-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  660nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059966(7-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  661nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed