BDBM50059968 2-(3-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-4-one::2-(3-fluorophenyl)-7-methyl-1,8-naphthyridin-4(1H)-one::CHEMBL51928

SMILES Cc1ccc2c(O)cc(nc2n1)-c1cccc(F)c1

InChI Key InChIKey=AFJQIXFUZDUCHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059968   

TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50059968(2-(3-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  530nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059968(2-(3-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed