BDBM50060138 CHEMBL324827::[(S)-1-{(4-Benzyloxy-benzyl)-[(2-phenyl-propylcarbamoyl)-methyl]-carbamoyl}-2-(3H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES CC(CNC(=O)CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)c1ccccc1

InChI Key InChIKey=KLNREZJWLLCYLH-RDFKHQOOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060138   

LigandPNGBDBM50060138(CHEMBL324827 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060138(CHEMBL324827 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  310nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed