BDBM50060140 CHEMBL115943::[(S)-1-{(4-Benzyloxy-benzyl)-[(2-cyano-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-2-(3H-imidazol-4-yl)-ethyl]-carbamic acid benzyl ester

SMILES O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCC(C#N)c1ccccc1

InChI Key InChIKey=SMBHALUVUUYXQI-CRGCAJGSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060140   

TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060140(CHEMBL115943 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-cy...)
Affinity DataIC50:  190nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060140(CHEMBL115943 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-cy...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed