BDBM50060446 (Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl)-hept-5-enoic acid::7-(2-Benzoylamino-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl)-hept-5-enoic acid::CHEMBL79413

SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1ccccc1)[C@@H](C\C=C/CCCC(O)=O)C2

InChI Key InChIKey=MIWWWWRKAQVMDU-YKEBRPLOSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060446   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060446((Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-b...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060446((Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-b...)
Affinity DataIC50:  810nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060446((Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-b...)
Affinity DataIC50:  360nMAssay Description:Concentration required to inhibit the PGD-2 evoked cAMP formation in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060446((Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-b...)
Affinity DataIC50:  360nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060446((Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-b...)
Affinity DataIC50:  5.20E+3nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]-PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060446((Z)-7-((1R,2R,3S,5S)-2-Benzoylamino-6,6-dimethyl-b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed