BDBM50060461 (+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::(Z)-7-[(1S,2R,3R,4R)-3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::CHEMBL309835

SMILES OC(=O)CCC\C=C/C[C@@H]1[C@H]2CC[C@H](C2)[C@H]1NS(=O)(=O)c1ccc2oc3ccccc3c2c1

InChI Key InChIKey=ABGGBXIEVBJCCD-DUMHOLGYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060461   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060461((+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2....)
Affinity DataIC50:  130nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060461((+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2....)
Affinity DataIC50:  70nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060461((+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2....)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of [3H]- PGD-2 radioligand binding to prostaglandin D2 receptor on human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060461((+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2....)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060461((+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2....)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of cAMP formation evoked by prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50060461((+) 7-[3-(Dibenzofuran-2-sulfonylamino)-bicyclo[2....)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed