BDBM50060582 1,10-Bis(trimethyl ammonium)decane dibromide::1,10-bis-(trimethyl ammonium) decane dibromide::CHEMBL1134::DECAMETHONIUM::DECAMETHONIUM BROMIDE::Decamethonium Iodide::N,N,N'',N''-Tetramethyl-decane-1,10-diammonium; dibromide::N,N,N,N'',N'',N''-Hexamethyldecane-1,10-diammoniumdibromide::Syncurine::decane-1,10-bis(trimethylammonium bromide)

SMILES C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C

InChI Key InChIKey=MTCUAOILFDZKCO-UHFFFAOYSA-N

Data  15 KI  5 IC50  2 ITC

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50060582   

TargetPhospholipase B(Cryptococcus neoformans)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Cryptococccus neoformans H99 PLB1activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Torpedo marmorata (Marbled electric ray))
UniversitÉ

LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
Affinity DataIC50:  1.06E+3nMpH: 4.0 T: 2°CAssay Description:The inhibitory activity of the equilibrated mixtures was determined. The activity of AChE was monitored by following the linear change in absorbance...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
Affinity DataIC50:  820nMAssay Description:Inhibition of histone H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 50060582   

HostPNGBDBM4((1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23...)
Lund University

GuestPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
ITC DataΔG°: -4.06kcal/mole −TΔS°: 1.84kcal/mole ΔH°: -5.97kcal/mole logk: 764
T: 35.05°C 
HostPNGBDBM11(beta-cyclodextrin | betadex)
Lund University

GuestPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
ITC DataΔG°: -3.01kcal/mole −TΔS°: -1.88kcal/mole ΔH°: -1.12kcal/mole logk: 137
T: 35.05°C