BDBM50060582 1,10-Bis(trimethyl ammonium)decane dibromide::1,10-bis-(trimethyl ammonium) decane dibromide::CHEMBL1134::DECAMETHONIUM::DECAMETHONIUM BROMIDE::Decamethonium Iodide::N,N,N'',N''-Tetramethyl-decane-1,10-diammonium; dibromide::N,N,N,N'',N'',N''-Hexamethyldecane-1,10-diammoniumdibromide::Syncurine::decane-1,10-bis(trimethylammonium bromide)
SMILES C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
InChI Key InChIKey=MTCUAOILFDZKCO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50060582
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Cryptococccus neoformans H99 PLB1activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMpH: 4.0 T: 2°CAssay Description:The inhibitory activity of the equilibrated mixtures was determined. The activity of AChE was monitored by following the linear change in absorbance...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of histone H3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 50060582
ITC DataΔG°: -4.06kcal/mole −TΔS°: 1.84kcal/mole ΔH°: -5.97kcal/mole logk: 764
T: 35.05°C
T: 35.05°C
ITC DataΔG°: -3.01kcal/mole −TΔS°: -1.88kcal/mole ΔH°: -1.12kcal/mole logk: 137
T: 35.05°C
T: 35.05°C