BDBM50061098 CHEMBL3393534::US9732087, 1

SMILES CN[C@@H]1CCN(C1)c1ccnc(NC2CC3CCC2C3)c1

InChI Key InChIKey=WGDVNAMQYXMAJQ-SWAPUOLTSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061098   

TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50061098(CHEMBL3393534 | US9732087, 1)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50061098(CHEMBL3393534 | US9732087, 1)
Affinity DataKi:  1nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50061098(CHEMBL3393534 | US9732087, 1)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed