BDBM50061304 2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]-1-[4-(2,4,6-trimethyl-phenyl)-piperazin-1-yl]-ethanone::CHEMBL128699

SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)c3c(C)cc(C)cc3C)cc12

InChI Key InChIKey=CPPNLMBHDVESPV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061304   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061304(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  1.40nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061304(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  1.90nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061304(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataKi:  117nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061304(2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at 5-hydroxytryptamine 1B receptor by measuring the inhibition of forskolin-stimulated cAMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed