BDBM50061814 1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-3-yl-ethanone::CHEMBL336824

SMILES Clc1ccc2c(-[#6]-[#6]-c3cc(Br)cnc3\[#6]-2=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6]-c2cccnc2)c1

InChI Key InChIKey=VEUVTUXBZCCPJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061814   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061814(1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50:  160nMAssay Description:Compound was tested for the inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50061814(1-[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclo...)
Affinity DataIC50: >4.00E+4nMAssay Description:Compound was tested for the inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed