BDBM50062412 5-(4-Methoxy-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL103468

SMILES COc1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key InChIKey=BVWMDHAJHGNBDE-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062412   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062412(5-(4-Methoxy-phenyl)-2,2,4-trimethyl-2,5-dihydro-1...)
Affinity DataKi:  13nMAssay Description:The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062412(5-(4-Methoxy-phenyl)-2,2,4-trimethyl-2,5-dihydro-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity to the human progesterone receptor(hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062412(5-(4-Methoxy-phenyl)-2,2,4-trimethyl-2,5-dihydro-1...)
Affinity DataIC50:  105nMAssay Description:Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed