BDBM50062915 CHEMBL827::METHYLPHENIDATE::methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate::methyl (R)-phenyl[(R)-piperidin-2-yl]acetate

SMILES COC(=O)[C@@H]([C@H]1CCCCN1)c1ccccc1

InChI Key InChIKey=DUGOZIWVEXMGBE-CHWSQXEVSA-N

Data  5 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50062915   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi:  125nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNorepinephrine transporter(RAT)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed