BDBM50063132 (R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfonylamino)-butyric acid::CHEMBL440921

SMILES CSc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C(C)C)C(O)=O

InChI Key InChIKey=JDHBSANRAFEDMI-QGZVFWFLSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50063132   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against endothelin converting enzyme (ECE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063132((R)-3-Methyl-2-(4'-methylsulfanyl-biphenyl-4-sulfo...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed