BDBM50063164 (R)-3-Methyl-2-(5-p-tolylethynyl-thiophene-2-sulfonylamino)-butyric acid::CHEMBL298699

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(s1)C#Cc1ccc(C)cc1)C(O)=O

InChI Key InChIKey=MAMDBBMJAYDZQJ-QGZVFWFLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063164   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063164((R)-3-Methyl-2-(5-p-tolylethynyl-thiophene-2-sulfo...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063164((R)-3-Methyl-2-(5-p-tolylethynyl-thiophene-2-sulfo...)
Affinity DataIC50:  5.90nMAssay Description:Inhibitory activity against Matrix metalloproteinase-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063164((R)-3-Methyl-2-(5-p-tolylethynyl-thiophene-2-sulfo...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against human gelatinase A (matrix metalloproteinase-2 MMP2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50063164((R)-3-Methyl-2-(5-p-tolylethynyl-thiophene-2-sulfo...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against Matrix metalloproteinase-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed